BDBM50188295 (R,S)-4-methyl-2-[3'-(2-piperazin-1-yl-thiazol-4-yl)-biphenyl-3-yl]-pentanoic acid cyanomethyl-amide::CHEMBL212907

SMILES CC(C)CC(C(=O)NCC#N)c1cccc(c1)-c1cccc(c1)-c1csc(n1)N1CCNCC1

InChI Key InChIKey=OXTNJKCSQHCZQO-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50188295   

TargetCathepsin K(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50188295((R,S)-4-methyl-2-[3'-(2-piperazin-1-yl-thiazol-4-y...)
Affinity DataKi:  0.800nMAssay Description:Inhibition of human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50188295((R,S)-4-methyl-2-[3'-(2-piperazin-1-yl-thiazol-4-y...)
Affinity DataKi:  190nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50188295((R,S)-4-methyl-2-[3'-(2-piperazin-1-yl-thiazol-4-y...)
Affinity DataKi:  5.60E+3nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50188295((R,S)-4-methyl-2-[3'-(2-piperazin-1-yl-thiazol-4-y...)
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed