BDBM50188852 CHEMBL211734::rac-3-{1-[4-(4-fluoro-phenyl)-1-oxo-2,8-diaza-spiro[4.5]dec-8-yl]-cyclohexyl}-benzonitrile

SMILES Fc1ccc(cc1)C1CNC(=O)C11CCN(CC1)C1(CCCCC1)c1cccc(c1)C#N

InChI Key InChIKey=LFLDNVRJTVJSAC-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50188852   

TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188852(CHEMBL211734 | rac-3-{1-[4-(4-fluoro-phenyl)-1-oxo...)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed