BDBM50188871 4-(4-fluoro-phenyl)-8-(1-p-tolyl-cyclohexyl)-2,8-diaza-spiro[4.5]decan-1-one::CHEMBL439499

SMILES Cc1ccc(cc1)C1(CCCCC1)N1CCC2(CC1)C(CNC2=O)c1ccc(F)cc1

InChI Key InChIKey=HOSBRYYPJMPNCU-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50188871   

TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188871(4-(4-fluoro-phenyl)-8-(1-p-tolyl-cyclohexyl)-2,8-d...)
Affinity DataEC50:  1.47E+3nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188871(4-(4-fluoro-phenyl)-8-(1-p-tolyl-cyclohexyl)-2,8-d...)
Affinity DataEC50:  1.47E+3nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed