BDBM50189287 CHEMBL3827413::US9597326, Compound 11
SMILES COc1ccc(CCc2cnc3c(N)nc4cc(CCP(O)(O)=O)ccc4c3c2)c(C)c1
InChI Key InChIKey=QDIIZWCSEUFKCD-UHFFFAOYSA-N
Data 4 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50189287
TargetToll-like receptor 7(Homo sapiens (Human))
Genomics Institute Of Novartis Research Foundation
Curated by ChEMBL
Genomics Institute Of Novartis Research Foundation
Curated by ChEMBL
Affinity DataEC50: 90nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells incubated for 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetToll-like receptor 7(Homo sapiens (Human))
Genomics Institute Of Novartis Research Foundation
Curated by ChEMBL
Genomics Institute Of Novartis Research Foundation
Curated by ChEMBL
Affinity DataEC50: 90nMAssay Description:Human embryonic kidney 293 (HEK 293) cells were stably transfected with human TLR7 and an NF-kB-driven luciferase reporter vector (pNifty-Luciferase)...More data for this Ligand-Target Pair
TargetToll-like receptor 7(Homo sapiens (Human))
Genomics Institute Of Novartis Research Foundation
Curated by ChEMBL
Genomics Institute Of Novartis Research Foundation
Curated by ChEMBL
Affinity DataEC50: 400nMAssay Description:Agonist activity at TLR7 in human PBMC assessed as induction of IL-6 secretion in supernatant after 18 hrsMore data for this Ligand-Target Pair
TargetToll-like receptor 7(Mus musculus)
Genomics Institute Of Novartis Research Foundation
Curated by ChEMBL
Genomics Institute Of Novartis Research Foundation
Curated by ChEMBL
Affinity DataEC50: 130nMAssay Description:Agonist activity at TLR7 in Balb/c mouse splenocytes assessed as induction of IL-6 secretion in supernatant after 18 hrsMore data for this Ligand-Target Pair