BDBM50189452 (S)-2-((S)-6-amino-1-((S)-1-carboxy-2-(1H-indol-3-yl)ethylamino)-1-oxohexan-2-ylamino)-4-phenylbutanoic acid::CHEMBL212710::N~2~-[(1S)-1-carboxy-3-phenylpropyl]-L-lysyl-L-tryptophan

SMILES NCCCC[C@H](N[C@@H](CCc1ccccc1)C(O)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O

InChI Key InChIKey=JXNGDSIPMBNTNL-HJOGWXRNSA-N

Data  4 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50189452   

TargetAngiotensin-converting enzyme(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50189452((S)-2-((S)-6-amino-1-((S)-1-carboxy-2-(1H-indol-3-...)
Affinity DataKi:  9nMAssay Description:Inhibition of recombinant human ACE C-domain expressed in CHO cells using Cbz-Phe-His-Leu as substrate preincubated for 15 mins followed by substrate...More data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50189452((S)-2-((S)-6-amino-1-((S)-1-carboxy-2-(1H-indol-3-...)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of recombinant human ACE N-domain expressed in CHO cells using Cbz-Phe-His-Leu as substrate preincubated for 15 mins followed by substrate...More data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50189452((S)-2-((S)-6-amino-1-((S)-1-carboxy-2-(1H-indol-3-...)
Affinity DataKi:  7.00E+3nMAssay Description:Inhibition of testis ACE C domainMore data for this Ligand-Target Pair
TargetNeprilysin(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50189452((S)-2-((S)-6-amino-1-((S)-1-carboxy-2-(1H-indol-3-...)
Affinity DataKi: >1.50E+5nMAssay Description:Inhibition of hGH-8His-NEP expressed in CHO cells preincubated for 15 mins followed by MCA-RPPGFDAFK-(Dnp)-OH peptide substrate addition by fluoresce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed