BDBM50191616 8-Fluoro-3-{[3-(5-fluoro-1H-indol-3-yl)propyl](propyl)amino}-chromane-5-carboxamide::CHEMBL213652::rac-8-fluoro-3-{[3-(5-fluoro-1H-indol-3-yl)propyl](propyl)amino}chromane-5-carboxamide

SMILES CCCN(CCCc1c[nH]c2ccc(F)cc12)C1COc2c(F)ccc(C(N)=O)c2C1

InChI Key InChIKey=JNVDPIPWLMZECZ-UHFFFAOYSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50191616   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50191616(8-Fluoro-3-{[3-(5-fluoro-1H-indol-3-yl)propyl](pro...)
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50191616(8-Fluoro-3-{[3-(5-fluoro-1H-indol-3-yl)propyl](pro...)
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50191616(8-Fluoro-3-{[3-(5-fluoro-1H-indol-3-yl)propyl](pro...)
Affinity DataKi:  7.10nMAssay Description:Displacement of [3H]paroxetine from serotonin transporter in Sprague-Dawley rat frontal cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50191616(8-Fluoro-3-{[3-(5-fluoro-1H-indol-3-yl)propyl](pro...)
Affinity DataKi:  7.10nMAssay Description:Displacement of [3H]paroxetine from 5-HT transporter in Sprague-Dawley rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50191616(8-Fluoro-3-{[3-(5-fluoro-1H-indol-3-yl)propyl](pro...)
Affinity DataIC50:  128nMAssay Description:Inhibition of 5-HT transporter-mediated [3H]5HT uptake in human Jar cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50191616(8-Fluoro-3-{[3-(5-fluoro-1H-indol-3-yl)propyl](pro...)
Affinity DataIC50:  128nMAssay Description:Inhibition of [3H]5-HT uptake at human 5-HT transporter expressed in Jar cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed