BDBM50191616 8-Fluoro-3-{[3-(5-fluoro-1H-indol-3-yl)propyl](propyl)amino}-chromane-5-carboxamide::CHEMBL213652::rac-8-fluoro-3-{[3-(5-fluoro-1H-indol-3-yl)propyl](propyl)amino}chromane-5-carboxamide
SMILES CCCN(CCCc1c[nH]c2ccc(F)cc12)C1COc2c(F)ccc(C(N)=O)c2C1
InChI Key InChIKey=JNVDPIPWLMZECZ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50191616
Affinity DataKi: 3.5nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataKi: 7.10nMAssay Description:Displacement of [3H]paroxetine from serotonin transporter in Sprague-Dawley rat frontal cortical membraneMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataKi: 7.10nMAssay Description:Displacement of [3H]paroxetine from 5-HT transporter in Sprague-Dawley rat cortical membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 128nMAssay Description:Inhibition of 5-HT transporter-mediated [3H]5HT uptake in human Jar cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 128nMAssay Description:Inhibition of [3H]5-HT uptake at human 5-HT transporter expressed in Jar cellsMore data for this Ligand-Target Pair