BDBM50191626 (3R)-8-fluoro-3-[[3-(5-fluoro-1H-indol-3-yl)propyl](methyl)amino]chromane-5-carboxamide::CHEMBL386242

SMILES CN(CCCc1c[nH]c2ccc(F)cc12)[C@H]1COc2c(F)ccc(C(N)=O)c2C1

InChI Key InChIKey=YSOCJLRWGGPWKP-OAHLLOKOSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50191626   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50191626((3R)-8-fluoro-3-[[3-(5-fluoro-1H-indol-3-yl)propyl...)
Affinity DataKi:  14.8nMAssay Description:Displacement of [3H]paroxetine from 5-HT transporter in Sprague-Dawley rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50191626((3R)-8-fluoro-3-[[3-(5-fluoro-1H-indol-3-yl)propyl...)
Affinity DataKi:  266nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50191626((3R)-8-fluoro-3-[[3-(5-fluoro-1H-indol-3-yl)propyl...)
Affinity DataIC50:  116nMAssay Description:Inhibition of [3H]5-HT uptake at human 5-HT transporter expressed in Jar cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed