BDBM50191637 CHEMBL211480::rac-N-(cyclopropylmethyl)-N-[3-(5-fluoro-1H-indol-3-yl)propyl]-N-(5-methoxy-3,4-dihydro-2H-chromen-3-yl)amine
SMILES COc1cccc2OCC(Cc12)N(CCCc1c[nH]c2ccc(F)cc12)CC1CC1
InChI Key InChIKey=BKJSIAOCAXHNFA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50191637
Affinity DataKi: 1.68nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataKi: 4.30nMAssay Description:Displacement of [3H]paroxetine from 5-HT transporter in Sprague-Dawley rat cortical membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 42.6nMAssay Description:Inhibition of [3H]5-HT uptake at human 5-HT transporter expressed in Jar cellsMore data for this Ligand-Target Pair