BDBM50191836 4-(4-(4-methyl-1H-imidazol-5-yl)piperidin-1-yl)-5-o-tolylpyrimidine::CHEMBL215510

SMILES Cc1nc[nH]c1C1CCN(CC1)c1ncncc1-c1ccccc1C

InChI Key InChIKey=AAZYMKQLICKXJJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50191836   

TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50191836(4-(4-(4-methyl-1H-imidazol-5-yl)piperidin-1-yl)-5-...)
Affinity DataIC50:  250nMAssay Description:Inhibition of human NHE1 expressed in Ap1 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed