BDBM50191849 5-(3-chloro-4-fluorophenyl)-2-methoxy-4-(4-(4-methyl-1H-imidazol-5-yl)piperidin-1-yl)pyrimidine::CHEMBL385944

SMILES COc1ncc(-c2ccc(F)c(Cl)c2)c(n1)N1CCC(CC1)c1[nH]cnc1C

InChI Key InChIKey=UEOAEDYBCIOABB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50191849   

TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50191849(5-(3-chloro-4-fluorophenyl)-2-methoxy-4-(4-(4-meth...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human NHE1 expressed in Ap1 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed