BDBM50191974 CHEMBL3913766
SMILES CN1CCN(CC1)c1ccccc1CNC(=O)c1ccc(F)c(NC(=O)c2cnc3cc(ccn23)-c2cnn(C)c2)c1
InChI Key InChIKey=JJKABNROBRKPQT-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50191974
TargetPlatelet-derived growth factor receptor beta(Rattus norvegicus)
Novartis Institutes Of Biomedical Research (Nibr)
Curated by ChEMBL
Novartis Institutes Of Biomedical Research (Nibr)
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:Inhibition of PDGFR-beta driven proliferation of rat A10 cells after 68 hrs in presence of rat recombinant PDGF-BB by cell titer-glo luminescence ass...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Novartis Institutes Of Biomedical Research (Nibr)
Curated by ChEMBL
Novartis Institutes Of Biomedical Research (Nibr)
Curated by ChEMBL
Affinity DataIC50: 0.320nMAssay Description:Inhibition of PDGFRalpha kinase domain (unknown origin) assessed as reduction in probe peptide substrate phosphorylation by capillary electrophoresisMore data for this Ligand-Target Pair