BDBM50193079 CHEBI:5834::CHEMBL1237210

SMILES CC(C)C(=O)[C@@]12C(O)=C(CC=C(C)C)C(=O)[C@@](CC=C(C)C)(C[C@H](CC=C(C)C)[C@@]1(C)CCC=C(C)C)C2=O

InChI Key InChIKey=IWBJJCOKGLUQIZ-HQKKAZOISA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50193079   

TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50193079(CHEBI:5834 | CHEMBL1237210)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of recombinant human GST-tagged SIRT1 overexpressed in Escherichia coli DH5alpha assessed as deacetylation activity using [3H]-MPSDKTIGG a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Guru Jambheshwar University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50193079(CHEBI:5834 | CHEMBL1237210)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of recombinant human GST-tagged SIRT2 overexpressed in Escherichia coli DH5alpha assessed as deacetylation activity using [3H]-MPSDKTIGG a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Abdul Wali Khan University Mardan

Curated by ChEMBL
LigandPNGBDBM50193079(CHEBI:5834 | CHEMBL1237210)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of mPGES1 (unknown origin) assessed as reduction in conversion of PGH to PGE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Chinese Academy Of Medical Sciences And Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50193079(CHEBI:5834 | CHEMBL1237210)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of serotonin transporter (unknown origin) assessed as suppression of synaptosomal uptake of serotoninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Chinese Academy Of Medical Sciences And Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50193079(CHEBI:5834 | CHEMBL1237210)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of norepinephrine transporter (unknown origin) assessed as suppression of synaptosomal uptake of norepinephrineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Chinese Academy Of Medical Sciences And Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50193079(CHEBI:5834 | CHEMBL1237210)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of dopamine transporter (unknown origin) assessed as suppression of synaptosomal uptake of dopamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed