BDBM50193336 (E)-1-(4-chlorophenyl)-2-hydroxy-3-(4-pyridin-2-ylpiperazin-1-yl)propanon-1-one O-methyloxime::CHEMBL214247

SMILES CO\N=C(\C(O)CN1CCN(CC1)c1ccccn1)c1ccc(Cl)cc1

InChI Key InChIKey=QIVGZELWYADNGV-ZBJSNUHESA-N

Data  2 KI  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50193336   

TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193336((E)-1-(4-chlorophenyl)-2-hydroxy-3-(4-pyridin-2-yl...)
Affinity DataKi:  113nMAssay Description:Displacement of [3H]A-369508 from human recombinant D4.4 receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193336((E)-1-(4-chlorophenyl)-2-hydroxy-3-(4-pyridin-2-yl...)
Affinity DataKi:  995nMAssay Description:Displacement of [3H]PIPAT from human recombinant D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193336((E)-1-(4-chlorophenyl)-2-hydroxy-3-(4-pyridin-2-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human recombinant D2 receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193336((E)-1-(4-chlorophenyl)-2-hydroxy-3-(4-pyridin-2-yl...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant D2 receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193336((E)-1-(4-chlorophenyl)-2-hydroxy-3-(4-pyridin-2-yl...)
Affinity DataEC50:  46nMAssay Description:Activity at human recombinant D4.4 receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed