BDBM50193611 (E)-N-(4-(dimethylamino)-2-propylquinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)acrylamide::CHEMBL217575

SMILES CCCc1cc(N(C)C)c2cc(NC(=O)\C=C\c3ccc(cc3)C(F)(F)F)ccc2n1

InChI Key InChIKey=GNDQGVNJNAVFDD-MDWZMJQESA-N

Data  1 IC50  1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50193611   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50193611((E)-N-(4-(dimethylamino)-2-propylquinolin-6-yl)-3-...)
Show SMILES CCCc1cc(N(C)C)c2cc(NC(=O)\C=C\c3ccc(cc3)C(F)(F)F)ccc2n1
Show InChI InChI=1S/C24H24F3N3O/c1-4-5-18-15-22(30(2)3)20-14-19(11-12-21(20)28-18)29-23(31)13-8-16-6-9-17(10-7-16)24(25,26)27/h6-15H,4-5H2,1-3H3,(H,29,31)/b13-8+
Affinity DataIC50: 43nMAssay Description:Displacement of 125I-[Phe13,Tyr19]-MCH from human MCH-R1More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50193611((E)-N-(4-(dimethylamino)-2-propylquinolin-6-yl)-3-...)
Show SMILES CCCc1cc(N(C)C)c2cc(NC(=O)\C=C\c3ccc(cc3)C(F)(F)F)ccc2n1
Show InChI InChI=1S/C24H24F3N3O/c1-4-5-18-15-22(30(2)3)20-14-19(11-12-21(20)28-18)29-23(31)13-8-16-6-9-17(10-7-16)24(25,26)27/h6-15H,4-5H2,1-3H3,(H,29,31)/b13-8+
Affinity DataEC50:  300nMAssay Description:Stimulation of IP3-coupled mobilization of calcium in HEK293 cells expressing MCH-R1More data for this Ligand-Target Pair