BDBM50193653 (E)-N-(4-amino-2-butylquinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)acrylamide::CHEMBL384765

SMILES CCCCc1cc(N)c2cc(NC(=O)\C=C\c3ccc(cc3)C(F)(F)F)ccc2n1

InChI Key InChIKey=FYVMTTJUMRLJMT-KPKJPENVSA-N

Data  1 IC50  1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50193653   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50193653((E)-N-(4-amino-2-butylquinolin-6-yl)-3-(4-(trifluo...)
Show SMILES CCCCc1cc(N)c2cc(NC(=O)\C=C\c3ccc(cc3)C(F)(F)F)ccc2n1
Show InChI InChI=1S/C23H22F3N3O/c1-2-3-4-17-14-20(27)19-13-18(10-11-21(19)28-17)29-22(30)12-7-15-5-8-16(9-6-15)23(24,25)26/h5-14H,2-4H2,1H3,(H2,27,28)(H,29,30)/b12-7+
Affinity DataIC50: 1.5nMAssay Description:Displacement of 125I-[Phe13,Tyr19]-MCH from human MCH-R1More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50193653((E)-N-(4-amino-2-butylquinolin-6-yl)-3-(4-(trifluo...)
Show SMILES CCCCc1cc(N)c2cc(NC(=O)\C=C\c3ccc(cc3)C(F)(F)F)ccc2n1
Show InChI InChI=1S/C23H22F3N3O/c1-2-3-4-17-14-20(27)19-13-18(10-11-21(19)28-17)29-22(30)12-7-15-5-8-16(9-6-15)23(24,25)26/h5-14H,2-4H2,1H3,(H2,27,28)(H,29,30)/b12-7+
Affinity DataEC50:  210nMAssay Description:Stimulation of IP3-coupled mobilization of calcium in HEK293 cells expressing MCH-R1More data for this Ligand-Target Pair