BDBM50194242 CHEMBL378082::H-Dmt-Tic-NH-CH[(CH2)4-NH-Ac]-Bid

SMILES CC(=O)NCCCCC(NC(=O)C1Cc2ccccc2CN1C(=O)C(N)Cc1c(C)cc(O)cc1C)c1nc2ccccc2[nH]1

InChI Key InChIKey=IOSGXZKTOLVOTQ-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50194242   

TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194242(CHEMBL378082 | H-Dmt-Tic-NH-CH[(CH2)4-NH-Ac]-Bid)
Affinity DataKi:  0.130nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
University Of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194242(CHEMBL378082 | H-Dmt-Tic-NH-CH[(CH2)4-NH-Ac]-Bid)
Affinity DataKi:  0.180nMAssay Description:Displacement of [3H]deltorphin2 from delta opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194242(CHEMBL378082 | H-Dmt-Tic-NH-CH[(CH2)4-NH-Ac]-Bid)
Affinity DataIC50: >1.00E+4nMAssay Description:Agonist activity at delta opioid receptor assessed as inhibition of electrically-evoked contraction of mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194242(CHEMBL378082 | H-Dmt-Tic-NH-CH[(CH2)4-NH-Ac]-Bid)
Affinity DataIC50:  53.9nMAssay Description:Agonist activity at mu opioid receptor assessed as inhibition of electrically-evoked contraction of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed