BDBM50194244 CHEMBL212172::H-Dmt-Tic-NH-(D)-CH[(CH2)4-NH-Z]-Bid

SMILES Cc1cc(O)cc(C)c1CC(N)C(=O)N1Cc2ccccc2CC1C(=O)N[C@H](CCCCNC(=O)OCc1ccccc1)c1nc2ccccc2[nH]1

InChI Key InChIKey=ZHRKDWCBKIOLKI-QNUATKLTSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50194244   

TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194244(CHEMBL212172 | H-Dmt-Tic-NH-(D)-CH[(CH2)4-NH-Z]-Bi...)
Affinity DataKi:  0.150nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
University Of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194244(CHEMBL212172 | H-Dmt-Tic-NH-(D)-CH[(CH2)4-NH-Z]-Bi...)
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]deltorphin2 from delta opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194244(CHEMBL212172 | H-Dmt-Tic-NH-(D)-CH[(CH2)4-NH-Z]-Bi...)
Affinity DataIC50: >1.00E+4nMAssay Description:Agonist activity at delta opioid receptor assessed as inhibition of electrically-evoked contraction of mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Cagliari

Curated by ChEMBL
LigandPNGBDBM50194244(CHEMBL212172 | H-Dmt-Tic-NH-(D)-CH[(CH2)4-NH-Z]-Bi...)
Affinity DataIC50:  62.5nMAssay Description:Agonist activity at mu opioid receptor assessed as inhibition of electrically-evoked contraction of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed