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BDBM50194549 CHEMBL217222::N,N-diisopropyl-3-phenyl-4-(3-phenylpropanamido)-2-(pyridin-3-yl)butanamide

SMILES: CC(C)N(C(C)C)C(=O)C(C(CNC(=O)CCc1ccccc1)c1ccccc1)c1cccnc1

InChI Key: InChIKey=SBVQSSIMWONYEL-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50194549   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-gated potassium channel subunit Kv1.5


(Homo sapiens (Human))
BDBM50194549
PNG
(CHEMBL217222 | N,N-diisopropyl-3-phenyl-4-(3-pheny...)
Show SMILES CC(C)N(C(C)C)C(=O)C(C(CNC(=O)CCc1ccccc1)c1ccccc1)c1cccnc1
Show InChI InChI=1S/C30H37N3O2/c1-22(2)33(23(3)4)30(35)29(26-16-11-19-31-20-26)27(25-14-9-6-10-15-25)21-32-28(34)18-17-24-12-7-5-8-13-24/h5-16,19-20,22-23,27,29H,17-18,21H2,1-4H3,(H,32,34)
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 100n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of Kv1.5


Bioorg Med Chem Lett 16: 5897-901 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.054
BindingDB Entry DOI: 10.7270/Q2Z60NP6
More data for this
Ligand-Target Pair