BDBM501951 US11028075, Example 84
SMILES Fc1ccc(cc1C(F)(F)F)[C@H]1CC[C@H](Nc2cc(F)c(cc2F)S(=O)(=O)Nc2ccncn2)[C@H](C1)N1CCCC1
InChI Key InChIKey=ZYJAZKZKCCTNAJ-OWSXEPHWSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 501951
Affinity DataIC50: 0.520nMAssay Description:The following voltage clamp electrophysiology studies are performed on representative compounds using cells heterologously expressing Nav1.7 or Nav1....More data for this Ligand-Target Pair
Affinity DataIC50: 0.877nMAssay Description:Saturation experiments. A competitive NaV1.7 inhibitor having a methyl group is tritiated. Three tritiums are incorporated in place of methyl hydroge...More data for this Ligand-Target Pair