BDBM50195262 CHEMBL3966946::US11655221, Example 34::US20230278969, Example 34

SMILES O=C(N[C@@H](Cc1ccc(cc1)-c1ccc(cc1)C#N)C#N)C1CNCCCO1

InChI Key InChIKey=FCRODBUNBQJNPU-BGERDNNASA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50195262   

TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services

Curated by ChEMBL
LigandPNGBDBM50195262(CHEMBL3966946 | US11655221, Example 34 | US2023027...)
Affinity DataIC50:  63nMAssay Description:Inhibition of human recombinant DPP1 using Gly-Arg-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services

Curated by ChEMBL
LigandPNGBDBM50195262(CHEMBL3966946 | US11655221, Example 34 | US2023027...)
Affinity DataIC50:  60.3nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services

Curated by ChEMBL
LigandPNGBDBM50195262(CHEMBL3966946 | US11655221, Example 34 | US2023027...)
Affinity DataIC50:  60.3nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In DepthDetails US Patent