BDBM50195934 CHEMBL3977256

SMILES CC(C)CC(NC(=O)C(CO)NC(=O)OCc1ccccc1)C(=O)NC(Cc1ccc(O)cc1)C(N)=O

InChI Key InChIKey=NEKDVAUWQXAURL-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50195934   

TargetProteasome subunit beta type-5(Homo sapiens (Human))
University Of Naples Federico Ii

Curated by ChEMBL
LigandPNGBDBM50195934(CHEMBL3977256)
Affinity DataKi:  2.18E+3nMAssay Description:Competitive inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-Leu-Leu-Val-Tyr-AMC as substrate measured for 10 mins by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Naples Federico Ii

Curated by ChEMBL
LigandPNGBDBM50195934(CHEMBL3977256)
Affinity DataKi:  8.59E+3nMAssay Description:Competitive inhibition of post-glutamyl peptide hydrolyzing activity of human 20S proteasome using Cbz-Leu-Leu-Glu-AMC as substrate measured for 10 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed