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BDBM50196035 CHEMBL214965::N-phenyl-2,3,4-trihydroxy-5-benzyl-benzamide

SMILES: Oc1c(O)c(Cc2ccccc2)cc(C(=O)Nc2ccccc2)c1O

InChI Key: InChIKey=QFCGWKILQYTRID-UHFFFAOYSA-N

Data: 1 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50196035   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Apoptosis regulator Bcl-2


(Homo sapiens (Human))
BDBM50196035
PNG
(CHEMBL214965 | N-phenyl-2,3,4-trihydroxy-5-benzyl-...)
Show SMILES Oc1c(O)c(Cc2ccccc2)cc(C(=O)Nc2ccccc2)c1O
Show InChI InChI=1S/C20H17NO4/c22-17-14(11-13-7-3-1-4-8-13)12-16(18(23)19(17)24)20(25)21-15-9-5-2-6-10-15/h1-10,12,22-24H,11H2,(H,21,25)
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Article
PubMed
8.30E+3n/an/an/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Displacement of FAM-Bid from human Bcl2 by FP assay


J Med Chem 49: 6139-42 (2006)


Article DOI: 10.1021/jm060460o
BindingDB Entry DOI: 10.7270/Q24M946T
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2


(Homo sapiens (Human))
BDBM50196035
PNG
(CHEMBL214965 | N-phenyl-2,3,4-trihydroxy-5-benzyl-...)
Show SMILES Oc1c(O)c(Cc2ccccc2)cc(C(=O)Nc2ccccc2)c1O
Show InChI InChI=1S/C20H17NO4/c22-17-14(11-13-7-3-1-4-8-13)12-16(18(23)19(17)24)20(25)21-15-9-5-2-6-10-15/h1-10,12,22-24H,11H2,(H,21,25)
PDB

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Article
PubMed
n/an/a 5.00E+3n/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Inhibition of growth of human PC3 cell overexpressing Bcl2


J Med Chem 49: 6139-42 (2006)


Article DOI: 10.1021/jm060460o
BindingDB Entry DOI: 10.7270/Q24M946T
More data for this
Ligand-Target Pair
Apoptosis regulator Bcl-2


(Homo sapiens (Human))
BDBM50196035
PNG
(CHEMBL214965 | N-phenyl-2,3,4-trihydroxy-5-benzyl-...)
Show SMILES Oc1c(O)c(Cc2ccccc2)cc(C(=O)Nc2ccccc2)c1O
Show InChI InChI=1S/C20H17NO4/c22-17-14(11-13-7-3-1-4-8-13)12-16(18(23)19(17)24)20(25)21-15-9-5-2-6-10-15/h1-10,12,22-24H,11H2,(H,21,25)
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


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Article
PubMed
n/an/a 7.20E+3n/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Binding affinity to human Bcl2 by ELISA


J Med Chem 49: 6139-42 (2006)


Article DOI: 10.1021/jm060460o
BindingDB Entry DOI: 10.7270/Q24M946T
More data for this
Ligand-Target Pair