BDBM50196106 CHEMBL216197::N-(2-diethylaminoethyl)-N'-(3-ethyl-2,8-dimethylquinolin-4-yl)benzene-1,4-diamine

SMILES CCN(CC)CCNc1ccc(Nc2c(CC)c(C)nc3c(C)cccc23)cc1

InChI Key InChIKey=VWHNYSUZLOHFTG-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50196106   

TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Juvantia Pharma

Curated by ChEMBL
LigandPNGBDBM50196106(CHEMBL216197 | N-(2-diethylaminoethyl)-N'-(3-ethyl...)
Affinity DataKi:  82nMAssay Description:Displacement of [3H]rauwolscine from human ADRA2C expressed in S115 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Juvantia Pharma

Curated by ChEMBL
LigandPNGBDBM50196106(CHEMBL216197 | N-(2-diethylaminoethyl)-N'-(3-ethyl...)
Affinity DataKi:  82.0nMAssay Description:Binding affinity to human cloned Alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Juvantia Pharma

Curated by ChEMBL
LigandPNGBDBM50196106(CHEMBL216197 | N-(2-diethylaminoethyl)-N'-(3-ethyl...)
Affinity DataKi:  900nMAssay Description:Displacement of [3H]rauwolscine from human ADRA2A expressed in S115 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Juvantia Pharma

Curated by ChEMBL
LigandPNGBDBM50196106(CHEMBL216197 | N-(2-diethylaminoethyl)-N'-(3-ethyl...)
Affinity DataKi:  2.90E+3nMAssay Description:Displacement of [3H]rauwolscine from human ADRA2B expressed in S115 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed