BDBM50196137 CHEMBL216399::[4-(4-methylpiperazin-1-yl)phenyl]-(2-methylquinolin-4-yl)-amine

SMILES CN1CCN(CC1)c1ccc(Nc2cc(C)nc3ccccc23)cc1

InChI Key InChIKey=MKIZKMFJTXEUHC-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50196137   

TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Juvantia Pharma

Curated by ChEMBL
LigandPNGBDBM50196137(CHEMBL216399 | [4-(4-methylpiperazin-1-yl)phenyl]-...)
Affinity DataKi:  500nMAssay Description:Displacement of [3H]rauwolscine from human ADRA2A expressed in S115 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Juvantia Pharma

Curated by ChEMBL
LigandPNGBDBM50196137(CHEMBL216399 | [4-(4-methylpiperazin-1-yl)phenyl]-...)
Affinity DataKi:  690nMAssay Description:Displacement of [3H]rauwolscine from human ADRA2C expressed in S115 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Juvantia Pharma

Curated by ChEMBL
LigandPNGBDBM50196137(CHEMBL216399 | [4-(4-methylpiperazin-1-yl)phenyl]-...)
Affinity DataKi:  690nMAssay Description:Binding affinity to human cloned Alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Juvantia Pharma

Curated by ChEMBL
LigandPNGBDBM50196137(CHEMBL216399 | [4-(4-methylpiperazin-1-yl)phenyl]-...)
Affinity DataKi:  3.70E+3nMAssay Description:Displacement of [3H]rauwolscine from human ADRA2B expressed in S115 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed