BDBM50196394 CHEMBL3941880

SMILES Fc1cc(Oc2ccccn2)cc(c1)N1Cc2ccccc2S1(=O)=O

InChI Key InChIKey=LDMHZAQFLWCKDT-UHFFFAOYSA-N

Data  1 IC50  5 EC50

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50196394   

TargetFree fatty acid receptor 1(Homo sapiens (Human))
University of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50196394(CHEMBL3941880)
Show SMILES Fc1cc(Oc2ccccn2)cc(c1)N1Cc2ccccc2S1(=O)=O
Show InChI InChI=1S/C18H13FN2O3S/c19-14-9-15(11-16(10-14)24-18-7-3-4-8-20-18)21-12-13-5-1-2-6-17(13)25(21,22)23/h1-11H,12H2
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity against human FFA1 expressed in human Flp-In T-REx293 cells assessed as as reduction in TUG424-induced response by Fura2-AM dye b...More data for this Ligand-Target Pair
TargetFree fatty acid receptor 4(Mus musculus)
University of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50196394(CHEMBL3941880)
Show SMILES Fc1cc(Oc2ccccn2)cc(c1)N1Cc2ccccc2S1(=O)=O
Show InChI InChI=1S/C18H13FN2O3S/c19-14-9-15(11-16(10-14)24-18-7-3-4-8-20-18)21-12-13-5-1-2-6-17(13)25(21,22)23/h1-11H,12H2
Affinity DataEC50:  479nMAssay Description:Agonist activity mouse FFA4 by by BRET based beta-arrestin-2 interaction assayMore data for this Ligand-Target Pair
TargetFree fatty acid receptor 4(Mus musculus)
University of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50196394(CHEMBL3941880)
Show SMILES Fc1cc(Oc2ccccn2)cc(c1)N1Cc2ccccc2S1(=O)=O
Show InChI InChI=1S/C18H13FN2O3S/c19-14-9-15(11-16(10-14)24-18-7-3-4-8-20-18)21-12-13-5-1-2-6-17(13)25(21,22)23/h1-11H,12H2
Affinity DataEC50:  148nMAssay Description:Agonist activity mouse FFA4 by Gq-dependent calcium mobilization assayMore data for this Ligand-Target Pair
TargetFree fatty acid receptor 4(Homo sapiens (Human))
University of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50196394(CHEMBL3941880)
Show SMILES Fc1cc(Oc2ccccn2)cc(c1)N1Cc2ccccc2S1(=O)=O
Show InChI InChI=1S/C18H13FN2O3S/c19-14-9-15(11-16(10-14)24-18-7-3-4-8-20-18)21-12-13-5-1-2-6-17(13)25(21,22)23/h1-11H,12H2
Affinity DataEC50:  128nMAssay Description:Agonist activity at C-terminal YFP-tagged human FFA4 expressed in HEK293 cells in presence of coelentrazine h by BRET based beta-arrestin-2 interacti...More data for this Ligand-Target Pair
TargetFree fatty acid receptor 4(Homo sapiens (Human))
University of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50196394(CHEMBL3941880)
Show SMILES Fc1cc(Oc2ccccn2)cc(c1)N1Cc2ccccc2S1(=O)=O
Show InChI InChI=1S/C18H13FN2O3S/c19-14-9-15(11-16(10-14)24-18-7-3-4-8-20-18)21-12-13-5-1-2-6-17(13)25(21,22)23/h1-11H,12H2
Affinity DataEC50:  123nMAssay Description:Agonist activity at C-terminal YFP-tagged human FFA4 expressed in HEK293 cells in presence of coelentrazine h by BRET based beta-arrestin-2 interacti...More data for this Ligand-Target Pair
TargetFree fatty acid receptor 4(Homo sapiens (Human))
University of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50196394(CHEMBL3941880)
Show SMILES Fc1cc(Oc2ccccn2)cc(c1)N1Cc2ccccc2S1(=O)=O
Show InChI InChI=1S/C18H13FN2O3S/c19-14-9-15(11-16(10-14)24-18-7-3-4-8-20-18)21-12-13-5-1-2-6-17(13)25(21,22)23/h1-11H,12H2
Affinity DataEC50:  234nMAssay Description:Agonist activity at human FFA4 expressed in human Flp-In T-REx293 cells by Fura2-AM dye based calcium mobilization assayMore data for this Ligand-Target Pair