BDBM50198082 CHEMBL3904239
SMILES CCc1ccc(cc1)\N=C1/S\C(=C/c2ccnc(Nc3ccc(cc3)C(O)=O)c2)C(=O)N1C
InChI Key InChIKey=KSWDUVDWZMIXGY-ZMSDRGEISA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50198082
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
University Of Berne
Curated by ChEMBL
University Of Berne
Curated by ChEMBL
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of Aurora-B/INCENP (unknown origin) using biotinylated STK2 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.20nMAssay Description:Inhibition of His-tagged human Aurora A kinase (122 to 40 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cells using biotinylated STK2 su...More data for this Ligand-Target Pair