BDBM50198789 4-(7-(4-fluoro-2-methylphenyl)-6-methylbenzo[e][1,2,4]triazin-3-ylamino)-N-(2-(pyrrolidin-1-yl)ethyl)benzenesulfonamide::CHEMBL397691::US8481536, 460::US8481536, 601

SMILES Cc1cc(F)ccc1-c1cc2nnc(Nc3ccc(cc3)S(=O)(=O)NCCN3CCCC3)nc2cc1C

InChI Key InChIKey=JUGGLTJXSGBAFT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50198789   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

US Patent
LigandPNGBDBM50198789(4-(7-(4-fluoro-2-methylphenyl)-6-methylbenzo[e][1,...)
Affinity DataIC50:  20.4nMT: 2°CAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

US Patent
LigandPNGBDBM50198789(4-(7-(4-fluoro-2-methylphenyl)-6-methylbenzo[e][1,...)
Affinity DataIC50:  20nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Targegen

US Patent
LigandPNGBDBM50198789(4-(7-(4-fluoro-2-methylphenyl)-6-methylbenzo[e][1,...)
Affinity DataIC50:  73.7nMAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent