BDBM50198820 CHEMBL231251::N-(7-(2,6-dimethylphenyl)-3-(4-(2-(pyrrolidin-1-yl)ethoxy)phenylamino)benzo[e][1,2,4]triazin-5-yl)acetamide::US8481536, 436::US8481536, 592

SMILES CC(=O)Nc1cc(cc2nnc(Nc3ccc(OCCN4CCCC4)cc3)nc12)-c1c(C)cccc1C

InChI Key InChIKey=BCAHGWFHBBMPHP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50198820   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

US Patent
LigandPNGBDBM50198820(CHEMBL231251 | N-(7-(2,6-dimethylphenyl)-3-(4-(2-(...)
Affinity DataIC50:  6.80nMT: 2°CAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Targegen

US Patent
LigandPNGBDBM50198820(CHEMBL231251 | N-(7-(2,6-dimethylphenyl)-3-(4-(2-(...)
Affinity DataIC50:  14nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Targegen

US Patent
LigandPNGBDBM50198820(CHEMBL231251 | N-(7-(2,6-dimethylphenyl)-3-(4-(2-(...)
Affinity DataIC50:  11.5nMAssay Description:Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.More data for this Ligand-Target Pair
In DepthDetails US Patent