BDBM50199289 (R)-8-ethyl-2-(4-hydroxybicyclo[2.2.2]octan-1-yl)-4-propyl-7,8-dihydro-1H-imidazo[1,2-g]purin-5(4H)-one::CHEMBL450341

SMILES CCCn1c2nc(nc2c2N[C@H](CC)Cn2c1=O)C12CCC(O)(CC1)CC2

InChI Key InChIKey=WYHPLEBRFOHMGR-JYMLRBTQSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50199289   

TargetAdenosine receptor A1(Rattus norvegicus (rat))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50199289((R)-8-ethyl-2-(4-hydroxybicyclo[2.2.2]octan-1-yl)-...)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]DPCPX from adenosine A1 receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50199289((R)-8-ethyl-2-(4-hydroxybicyclo[2.2.2]octan-1-yl)-...)
Affinity DataKi:  22nMAssay Description:Displacement of [125I]ABA from human adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50199289((R)-8-ethyl-2-(4-hydroxybicyclo[2.2.2]octan-1-yl)-...)
Affinity DataKi:  580nMAssay Description:Displacement of [125I]3-(4-aminobenzyl)-8-phenyloxyacetate-1-propyl-xanthine from human adenosine A2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50199289((R)-8-ethyl-2-(4-hydroxybicyclo[2.2.2]octan-1-yl)-...)
Affinity DataKi:  2.70E+3nMAssay Description:Displacement of [3H]ZM241385 from adenosine A2A receptor in rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50199289((R)-8-ethyl-2-(4-hydroxybicyclo[2.2.2]octan-1-yl)-...)
Affinity DataKi:  4.40E+3nMAssay Description:Displacement of [125I]ZM241385 from human adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50199289((R)-8-ethyl-2-(4-hydroxybicyclo[2.2.2]octan-1-yl)-...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]ABA from human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed