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BDBM50199384 (9R,12R,15S)-12-isopropyl-9-methyl-15-propyl-6,7,8,9,11,12,14,15,17,18-decahydro-5-oxa-8,11,14,17-tetraaza-benzocyclooctadecene-10,13,16-trione::CHEMBL425255

SMILES: CCC[C@@H]1NC(=O)[C@H](NC(=O)[C@@H](C)NCCOc2ccccc2\C=C\CNC1=O)C(C)C

InChI Key: InChIKey=ZVFAGNKUXGGANI-OCFNDUIGSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50199384   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Motilin receptor


(Homo sapiens (Human))
BDBM50199384
PNG
((9R,12R,15S)-12-isopropyl-9-methyl-15-propyl-6,7,8...)
Show SMILES CCC[C@@H]1NC(=O)[C@H](NC(=O)[C@@H](C)NCCOc2ccccc2\C=C\CNC1=O)C(C)C
Show InChI InChI=1S/C24H36N4O4/c1-5-9-19-23(30)26-13-8-11-18-10-6-7-12-20(18)32-15-14-25-17(4)22(29)28-21(16(2)3)24(31)27-19/h6-8,10-12,16-17,19,21,25H,5,9,13-15H2,1-4H3,(H,26,30)(H,27,31)(H,28,29)/b11-8+/t17-,19+,21-/m1/s1
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Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Tranzyme Pharma Inc.

Curated by ChEMBL


Assay Description
Displacement of [125I]motilin from human MOTR


J Med Chem 49: 7190-7 (2006)


Article DOI: 10.1021/jm0606600
BindingDB Entry DOI: 10.7270/Q2251JZH
More data for this
Ligand-Target Pair