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BDBM50199560 6-methoxy-8-[methyl-(1-methyl-pyrrolidin-3-yl)-amino]-4-oxo-1,4-dihydroquinoline-2-carboxylic acid (4-morpholin-4-yl-phenyl)amide::CHEMBL389068

SMILES: COc1cc(N(C)C2CCN(C)C2)c2nc(cc(O)c2c1)C(=O)Nc1ccc(cc1)N1CCOCC1

InChI Key: InChIKey=CCKNGITYOWMMON-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50199560   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 1B


(Homo sapiens (Human))
BDBM50199560
PNG
(6-methoxy-8-[methyl-(1-methyl-pyrrolidin-3-yl)-ami...)
Show SMILES COc1cc(N(C)C2CCN(C)C2)c2nc(cc(O)c2c1)C(=O)Nc1ccc(cc1)N1CCOCC1
Show InChI InChI=1S/C27H33N5O4/c1-30-9-8-20(17-30)31(2)24-15-21(35-3)14-22-25(33)16-23(29-26(22)24)27(34)28-18-4-6-19(7-5-18)32-10-12-36-13-11-32/h4-7,14-16,20H,8-13,17H2,1-3H3,(H,28,34)(H,29,33)
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Similars

Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



AstraZeneca Pharmaceuticals LP

Curated by ChEMBL


Assay Description
Displacement of [3H]GR125743 from 5HT1B receptor transfected in CHO cells


Bioorg Med Chem 15: 939-50 (2006)


Article DOI: 10.1016/j.bmc.2006.10.037
BindingDB Entry DOI: 10.7270/Q2445M3X
More data for this
Ligand-Target Pair