BDBM50199599 7-(3-(4-fluoropiperidin-1-yl)propoxy)-2-methyl-4-(3-(trifluoromethyl)phenyl)-1,2,3,4-tetrahydroisoquinoline::CHEMBL246747

SMILES CN1CC(c2cccc(c2)C(F)(F)F)c2ccc(OCCCN3CCC(F)CC3)cc2C1

InChI Key InChIKey=NZPOPKFDIKJIRC-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50199599   

TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50199599(7-(3-(4-fluoropiperidin-1-yl)propoxy)-2-methyl-4-(...)
Affinity DataKi:  11nMAssay Description:Binding affinity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50199599(7-(3-(4-fluoropiperidin-1-yl)propoxy)-2-methyl-4-(...)
Affinity DataKi:  15nMAssay Description:Binding affinity at human SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50199599(7-(3-(4-fluoropiperidin-1-yl)propoxy)-2-methyl-4-(...)
Affinity DataKi:  30nMAssay Description:Binding affinity at rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed