BDBM50199606 4-(7-(3-(4-fluoropiperidin-1-yl)propoxy)-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzonitrile::CHEMBL246748

SMILES CN1CC(c2ccc(cc2)C#N)c2ccc(OCCCN3CCC(F)CC3)cc2C1

InChI Key InChIKey=ZOTDNNWAQBXDPK-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50199606   

TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50199606(4-(7-(3-(4-fluoropiperidin-1-yl)propoxy)-2-methyl-...)
Affinity DataKi:  3.5nMAssay Description:Binding affinity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50199606(4-(7-(3-(4-fluoropiperidin-1-yl)propoxy)-2-methyl-...)
Affinity DataKi:  7.80nMAssay Description:Binding affinity at rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50199606(4-(7-(3-(4-fluoropiperidin-1-yl)propoxy)-2-methyl-...)
Affinity DataKi:  16nMAssay Description:Binding affinity at human SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed