BDBM50199865 (S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)-1-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)pyrrolidine-2-carboxamide::CHEMBL412923

SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

InChI Key InChIKey=GQKWRERWSHSLFH-MCEBTLFFSA-N

Data  5 KI  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50199865   

TargetMu-type opioid receptor(Rattus norvegicus (rat))
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50199865((S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-y...)
Affinity DataKi:  0.0540nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain P2 synaptosomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50199865((S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-y...)
Affinity DataKi:  0.0590nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in human SHSY5Y cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50199865((S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-y...)
Affinity DataKi:  0.0670nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50199865((S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-y...)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]DAMGO from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50199865((S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-y...)
Affinity DataKi:  5.60nMAssay Description:Displacement of [3H]deltorphin 2 from delta opioid receptor in rat brain P2 synaptosomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50199865((S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-y...)
Affinity DataEC50:  0.100nMAssay Description:Agonist activity at human MOR expressed in CHO cell membranes after 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50199865((S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-y...)
Affinity DataIC50:  0.430nMAssay Description:Agonist activity at mu opioid receptor in human SHSY5Y cells assessed as inhibition of forskolin-stimulated cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50199865((S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-y...)
Affinity DataIC50: >1.00E+4nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically evoked muscle contractionsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50199865((S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-y...)
Affinity DataIC50:  0.270nMAssay Description:Agonist activity at mu opioid receptor in Hartley guinea pig intestine assessed as inhibition of electrically evoked myenteric plexus longitudinal mu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed