BDBM502 2-({4-[bis(3-hydroxy-1,4-dioxo-1,4-dihydronaphthalen-2-yl)methyl]phenyl}(3-hydroxy-1,4-dioxo-1,4-dihydronaphthalen-2-yl)methyl)-3-hydroxy-1,4-dihydronaphthalene-1,4-dione::CHEMBL66033::Cancer Chemotherapy National Service Center (CCNSC) compound 117027::NSC 117027

SMILES Oc1c(O)c2ccccc2c(O)c1C(=C1C(=O)C(=O)c2ccccc2C1=O)c1ccc(cc1)C(C1C(=O)C(=O)c2ccccc2C1=O)C1C(=O)C(=O)c2ccccc2C1=O

InChI Key InChIKey=UPELKACGIHBTIT-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 502   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Institutes Of Health

LigandPNGBDBM502(2-({4-[bis(3-hydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50:  750nMpH: 6.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM502(2-({4-[bis(3-hydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibitory activity against HIV-1 integraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM502(2-({4-[bis(3-hydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50:  750nMAssay Description:Inhibitory activity against HIV-1 Protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM502(2-({4-[bis(3-hydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibitory activity against HIV-1 integraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM502(2-({4-[bis(3-hydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50:  6.00E+4nMAssay Description:Inhibitory activity against topoisomerase I.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed