BDBM50203530 (6S,7S)-N-hydroxy-6-{[4-(2-methyl-4-nitrophenyl)piperazin-1-yl]carbonyl}-5-azaspiro[2.5]octane-7-carboxamide::CHEMBL221120

SMILES Cc1cc(ccc1N1CCN(CC1)C(=O)[C@H]1NCC2(CC2)C[C@@H]1C(=O)NO)[N+]([O-])=O

InChI Key InChIKey=IWNGNUDBGMCFNB-RDJZCZTQSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50203530   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50203530((6S,7S)-N-hydroxy-6-{[4-(2-methyl-4-nitrophenyl)pi...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50203530((6S,7S)-N-hydroxy-6-{[4-(2-methyl-4-nitrophenyl)pi...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50203530((6S,7S)-N-hydroxy-6-{[4-(2-methyl-4-nitrophenyl)pi...)
Affinity DataIC50:  110nMAssay Description:Inhibition of ADAM10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50203530((6S,7S)-N-hydroxy-6-{[4-(2-methyl-4-nitrophenyl)pi...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50203530((6S,7S)-N-hydroxy-6-{[4-(2-methyl-4-nitrophenyl)pi...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50203530((6S,7S)-N-hydroxy-6-{[4-(2-methyl-4-nitrophenyl)pi...)
Affinity DataIC50:  160nMAssay Description:Inhibition of Her2 sheddase activity in BT474 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed