BDBM502055 N1,N2-dimethyl-N1-((3- (spiro[4.5]decan-8-yl)- 5,6-dihydro-4H- pyrrolo[1,2-b]pyrazol- 2-yl)methyl)ethane- 1,2-diamine::US11028083, Example 49

SMILES CNCCN(C)Cc1nn2CCCc2c1C1CCC2(CCCC2)CC1

InChI Key InChIKey=HDLMOUYGUDJTRP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 502055   

TargetProtein arginine N-methyltransferase 1(Homo sapiens)
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM502055(N1,N2-dimethyl-N1-((3- (spiro[4.5]decan-8-yl)- 5,6...)
Affinity DataIC50:  39nMAssay Description:This enzymatic assay was performed in a 384 well, white, low volume plate (PerkinElmer, Catalog 6008289) with assay buffer consisting of 50 mM Hepes ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM502055(N1,N2-dimethyl-N1-((3- (spiro[4.5]decan-8-yl)- 5,6...)
Affinity DataIC50:  74nMAssay Description:PRMT1,4,6: This enzymatic assay was performed in a 384 well, white, low volume plate (PerkinElmer, Catalog 6008289) with assay buffer consisting of 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM502055(N1,N2-dimethyl-N1-((3- (spiro[4.5]decan-8-yl)- 5,6...)
Affinity DataIC50:  114nMAssay Description:PRMT1,4,6: This enzymatic assay was performed in a 384 well, white, low volume plate (PerkinElmer, Catalog 6008289) with assay buffer consisting of 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 1(Homo sapiens)
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM502055(N1,N2-dimethyl-N1-((3- (spiro[4.5]decan-8-yl)- 5,6...)
Affinity DataIC50:  106nMAssay Description:PRMT1,4,6: This enzymatic assay was performed in a 384 well, white, low volume plate (PerkinElmer, Catalog 6008289) with assay buffer consisting of 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent