BDBM50206861 CHEMBL3928420

SMILES CCc1ccc(OCCNc2nc(Nc3cc(C)[nH]n3)cc(C)c2C#N)cn1

InChI Key InChIKey=NKWGBOOLJXYPQR-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50206861   

TargetAurora kinase A(Homo sapiens (Human))
Cxs

Curated by ChEMBL
LigandPNGBDBM50206861(CHEMBL3928420)
Affinity DataKi:  6nMAssay Description:Inhibition of recombinant Aurora A kinase derived from human Hela cells using kemptide as substrate in presence of [c-32P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Cxs

Curated by ChEMBL
LigandPNGBDBM50206861(CHEMBL3928420)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Cxs

Curated by ChEMBL
LigandPNGBDBM50206861(CHEMBL3928420)
Affinity DataIC50:  800nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Cxs

Curated by ChEMBL
LigandPNGBDBM50206861(CHEMBL3928420)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Cxs

Curated by ChEMBL
LigandPNGBDBM50206861(CHEMBL3928420)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Cxs

Curated by ChEMBL
LigandPNGBDBM50206861(CHEMBL3928420)
Affinity DataIC50:  4.60E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed