BDBM50208310 CHEMBL3883753
SMILES FC(F)Oc1ccc(cc1OC1CCCC1)C(=O)Nc1ccccc1Cl
InChI Key InChIKey=IOCQLERZNMLYQW-UHFFFAOYSA-N
Data 14 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50208310
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Southern Medical University
Curated by ChEMBL
Southern Medical University
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE3B using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Southern Medical University
Curated by ChEMBL
Southern Medical University
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of full length human PDE4C1 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Southern Medical University
Curated by ChEMBL
Southern Medical University
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE2A using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetCone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'(Homo sapiens (Human))
Southern Medical University
Curated by ChEMBL
Southern Medical University
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE6C using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
Southern Medical University
Curated by ChEMBL
Southern Medical University
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE11A using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Homo sapiens (Human))
Southern Medical University
Curated by ChEMBL
Southern Medical University
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE8A1 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Southern Medical University
Curated by ChEMBL
Southern Medical University
Curated by ChEMBL
Affinity DataIC50: 144nMAssay Description:Inhibition of full length human PDE4B1 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Southern Medical University
Curated by ChEMBL
Southern Medical University
Curated by ChEMBL
Affinity DataIC50: 95nMAssay Description:Inhibition of full length human PDE4A4 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A(Homo sapiens (Human))
Southern Medical University
Curated by ChEMBL
Southern Medical University
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE1A using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Southern Medical University
Curated by ChEMBL
Southern Medical University
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE10A2 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Southern Medical University
Curated by ChEMBL
Southern Medical University
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE7A using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Southern Medical University
Curated by ChEMBL
Southern Medical University
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE9A2 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Southern Medical University
Curated by ChEMBL
Southern Medical University
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of full length human PDE4D7 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Southern Medical University
Curated by ChEMBL
Southern Medical University
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE5A using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair