BDBM50209245 CHEMBL247378
SMILES [O-][N+](=O)c1cccc2cn[nH]c12
InChI Key InChIKey=PQCAUHUKTBHUSA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 21 hits for monomerid = 50209245
Affinity DataIC50: 2.87E+3nMAssay Description:Inhibitory activity against human neuronal nitric oxide synthase (nNOS)More data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Rattus norvegicus)
University Of Hradec Kralove
Curated by ChEMBL
University Of Hradec Kralove
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of nNOS in Wistar rat cortical homogenates incubated for 30 minsMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 2.12E+3nMAssay Description:Inhibitory activity against rat neuronal nitric oxide synthase (nNOS)More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:In vitro inhibitory concentration against rat cerebellar neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibition of human neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibition of human endothelial nitric oxide synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of rat neuronal NOSMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of rat brain recombinant nNOSMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of mouse recombinant iNOSMore data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of bovine recombinant eNOSMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Tested to inhibit the conversion of [3H]-L-arginine to [3H]-L-citrulline catalyzed by inducible NOS from mouse macrophage J774 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+4nMAssay Description:Tested to inhibit the conversion of [3H]-L-arginine to [3H]-L-citrulline catalyzed by inducible NOS from human DLD-1 cells.More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Tested to inhibit the conversion of [3H]-L-arginine to [3H]-L-citrulline catalyzed by neuronal NOS from rat cerebellum.More data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+4nMAssay Description:Tested to inhibit the conversion of [3H]-L-arginine to [3H]-L-citrulline catalyzed by endothelial NOS from human umbilical vein endothelial cells.More data for this Ligand-Target Pair
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of NOS2More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of nNOS in Sprague-Dawley rat brain homogenates assessed as conversion of oxyhemoglobin to methemoglobin measured for 10 mins by UV-visibl...More data for this Ligand-Target Pair
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli assessed as conversion of [gamma-14C]L-arginine to [14C]L-citrulline by radioacti...More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of mouse recombinant iNOS expressed in Escherichia coli assessed as conversion of [gamma-14C]L-arginine to [14C]L-citrulline by radioactiv...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of rat recombinant nNOS expressed in Saccharomyces cerevisiae assessed as conversion of [gamma-14C]L-arginine to [14C]L-citrulline by radi...More data for this Ligand-Target Pair
Affinity DataIC50: 1.89E+3nMAssay Description:Inhibitory activity against human endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair