BDBM50210854 CHEMBL3960040

SMILES Fc1cccc(CCn2c3CCCNC(=O)c3c3ccccc23)c1

InChI Key InChIKey=KRPJPNQVNAQLEE-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50210854   

TargetCholinesterase(Equus caballus (Horse))
University Of Bari&Quot;A. Moro&Quot

Curated by ChEMBL
LigandPNGBDBM50210854(CHEMBL3960040)
Affinity DataKi:  0.700nMAssay Description:Competitive inhibition of horse serum BChE in presence of varying levels of butyrylthiocholine iodide substrate by Lineweaver-burk plot methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Bari&Quot;A. Moro&Quot

Curated by ChEMBL
LigandPNGBDBM50210854(CHEMBL3960040)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of human BChE pretreated for 20 mins followed by butyrylthiocholine iodide substrate addition measured for 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
University Of Bari&Quot;A. Moro&Quot

Curated by ChEMBL
LigandPNGBDBM50210854(CHEMBL3960040)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of horse serum BChE pretreated for 20 mins followed by butyrylthiocholine iodide substrate addition measured for 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed