BDBM50211429 (4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)piperidin-1-yl)(4-methylpiperazin-1-yl)methanone::CHEMBL245534

SMILES CN1CCN(CC1)C(=O)N1CCC(CC1)Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12

InChI Key InChIKey=FBMRMTHKZVMVDV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50211429   

TargetTranscription factor Jun(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211429((4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)...)
Affinity DataIC50:  2.77E+3nMAssay Description:Inhibition of cJun translocation in IL1beta-stimulated A549 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211429((4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)...)
Affinity DataIC50:  5.28E+3nMAssay Description:Inhibition of CDK2 by IMAP technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211429((4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)...)
Affinity DataIC50:  18nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211429((4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)...)
Affinity DataIC50:  26nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed