BDBM50211885 5-(3,4-dihydroxybenzylidene)-3-phenyl-2-thioxothiazolidin-4-one::CHEMBL228097

SMILES Oc1ccc(\C=C2/SC(=S)N(C2=O)c2ccccc2)cc1O

InChI Key InChIKey=HRAFGHWKNFRMCY-ZROIWOOFSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50211885   

TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
Institute Of Science

Curated by ChEMBL
LigandPNGBDBM50211885(5-(3,4-dihydroxybenzylidene)-3-phenyl-2-thioxothia...)
Affinity DataKi:  4.20nMAssay Description:Inhibition of Plasmodium falciparum recombinant enoyl ACP reductase expressed in BL21 (DE3) cells with respect to crotonyl CoAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
Institute Of Science

Curated by ChEMBL
LigandPNGBDBM50211885(5-(3,4-dihydroxybenzylidene)-3-phenyl-2-thioxothia...)
Affinity DataKi:  32nMAssay Description:Inhibition of Plasmodium falciparum recombinant enoyl ACP reductase expressed in BL21 (DE3) cells with respect to NADHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-acyl-carrier protein reductase(Plasmodium falciparum)
Institute Of Science

Curated by ChEMBL
LigandPNGBDBM50211885(5-(3,4-dihydroxybenzylidene)-3-phenyl-2-thioxothia...)
Affinity DataIC50:  35nMAssay Description:Inhibition of Plasmodium falciparum recombinant enoyl ACP reductase expressed in BL21 (DE3) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed