BDBM50212687 2-(3-chloro-benzyl)-5-trifluoromethoxy-2,3-dihydro-isoindol-1-ylideneamine::CHEMBL247718

SMILES FC(F)(F)Oc1ccc2C(=N)N(Cc3cccc(Cl)c3)Cc2c1

InChI Key InChIKey=PVDYHVJORZHHLG-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50212687   

TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212687(2-(3-chloro-benzyl)-5-trifluoromethoxy-2,3-dihydro...)
Affinity DataKi:  8nMAssay Description:Binding affinity to NMDA NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212687(2-(3-chloro-benzyl)-5-trifluoromethoxy-2,3-dihydro...)
Affinity DataIC50:  49nMAssay Description:Antagonist activity at NMDA NR2B receptor assessed as calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed