BDBM50214935 5-fluoro-2-((Z)-(9-hydroxy-10-methoxy-2,2,4-trimethyl-1,2-dihydro-4aH-chromeno[3,4-f]quinolin-5(12aH)-ylidene)methyl)benzaldehyde oxime::CHEMBL232390
SMILES COc1c(O)ccc2OC(=Cc3ccc(F)cc3CN=O)C3=C(C=CC4NC(C)(C)C=C(C)C34)c12
InChI Key InChIKey=IDGUQWBWFLSKEX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50214935
Affinity DataKi: 1.5nMAssay Description:Displacement of radiolabeled dexamethasone from glucocorticoid receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Activity at GR assessed as repression of TNFalpha and IL 1beta induced E-selectin responseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Antagonist activity at GR assessed as inhibition of dexamethasone-induced GRE activationMore data for this Ligand-Target Pair
Affinity DataEC50: 356nMAssay Description:Agonist activity at GR by GRE activation assayMore data for this Ligand-Target Pair