BDBM50217731 CHEMBL396111::N-(2-chloro-4,5-dimethoxybenzyl)-4-(2-(4-hydroxybenzyl)-1H-indol-3-yl)-N-(4-((4-aminocyclohexyl)methyl)cyclohexyl)butanamide

SMILES COc1cc(Cl)c(CN(C2CCC(CC3CCC(N)CC3)CC2)C(=O)CCCc2c(Cc3ccc(O)cc3)[nH]c3ccccc23)cc1OC

InChI Key InChIKey=BIPSMDWSUSSJDS-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50217731   

TargetMelanocyte-stimulating hormone receptor(Mus musculus)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50217731(CHEMBL396111 | N-(2-chloro-4,5-dimethoxybenzyl)-4-...)
Affinity DataKi:  630nMAssay Description:Displacement of [125I]NDP-MSH from MC1 receptor in mouse B16 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50217731(CHEMBL396111 | N-(2-chloro-4,5-dimethoxybenzyl)-4-...)
Affinity DataKi:  1.90E+3nMAssay Description:Displacement of [125I]NDP-MSH from human recombinant MC4 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50217731(CHEMBL396111 | N-(2-chloro-4,5-dimethoxybenzyl)-4-...)
Affinity DataKi:  8.30E+3nMAssay Description:Displacement of [125I]NDP-MSH from human recombinant MC3 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50217731(CHEMBL396111 | N-(2-chloro-4,5-dimethoxybenzyl)-4-...)
Affinity DataKi:  1.10E+4nMAssay Description:Displacement of [125I]NDP-MSH from human recombinant MC5 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed