BDBM50217904 3-(5-chloro-thiophene-2-sulfonyl)-1-pyrrolidin-3-yl-1H-pyrrolo[2,3-b]pyridine::CHEMBL394233

SMILES Clc1ccc(CS(=O)(=O)c2cn(C3CCNC3)c3ncccc23)s1

InChI Key InChIKey=VZQAAXLQPHFJEF-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50217904   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50217904(3-(5-chloro-thiophene-2-sulfonyl)-1-pyrrolidin-3-y...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50217904(3-(5-chloro-thiophene-2-sulfonyl)-1-pyrrolidin-3-y...)
Affinity DataIC50:  11nMAssay Description:Antagonist activity at human 5HT6 expressed in HeLa cells assessed as intracellular cAMP level by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed