BDBM50218245 CHEMBL65799
SMILES COc1ccc(C(=O)Nc2c(Cl)cncc2Cl)c2cc(oc12)C#N
InChI Key InChIKey=ATETVUDHVLJVIY-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50218245
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Celltech-Chiroscience
Curated by ChEMBL
Celltech-Chiroscience
Curated by ChEMBL
Affinity DataIC50: 6.80nMAssay Description:Inhibition of Phosphodiesterase 4 from human U937 cellsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Celltech-Chiroscience
Curated by ChEMBL
Celltech-Chiroscience
Curated by ChEMBL
Affinity DataIC50: 6.80nMAssay Description:Inhibition of PDE4 in Homo sapiens (human) U937 cellsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Celltech-Chiroscience
Curated by ChEMBL
Celltech-Chiroscience
Curated by ChEMBL
Affinity DataIC50: 6.5nMAssay Description:Inhibition of rolipram binding to rat brain tissue at 20 uMMore data for this Ligand-Target Pair