BDBM50218282 (3R,4S)-ethyl 3-(2-chlorothiophene-5-carboxamido)-4-(4-(2-oxopyridin-1(2H)-yl)benzamido)pyrrolidine-1-carboxylate::CHEMBL437555
SMILES CCOC(=O)N1C[C@@H](NC(=O)c2ccc(Cl)s2)[C@H](C1)NC(=O)c1ccc(cc1)-n1ccccc1=O
InChI Key InChIKey=VCOPBIUVMSEQNG-ZWKOTPCHSA-N
Data 13 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50218282
Affinity DataKi: 0.5nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
Affinity DataKi: 0.730nMAssay Description:Inhibition of human factor 10a in presence of tripeptide substrate at 25 degCMore data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Inhibition of human factor 10a in presence of tripeptide substrate at 37 degCMore data for this Ligand-Target Pair
Affinity DataKi: 7.5nMAssay Description:Inhibition of human factor 10a in presence of prothrombin at 25 degCMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibition of human factor 10a in presence of saturating prothrombin at 37 degCMore data for this Ligand-Target Pair
Affinity DataKi: 4.02E+3nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: >6.00E+3nMAssay Description:Inhibition of human plasma kallikreinMore data for this Ligand-Target Pair
Affinity DataKi: 7.38E+3nMAssay Description:Inhibition of human factor 11aMore data for this Ligand-Target Pair
Affinity DataKi: >1.10E+4nMAssay Description:Inhibition of human factor 7aMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: >1.40E+4nMAssay Description:Inhibition of human urokinaseMore data for this Ligand-Target Pair
Affinity DataKi: >2.10E+4nMAssay Description:Inhibition of human activated protein CMore data for this Ligand-Target Pair
Affinity DataKi: >2.10E+4nMAssay Description:Inhibition of human tissue plasminogen activatorMore data for this Ligand-Target Pair
Affinity DataKi: >2.20E+4nMAssay Description:Inhibition of human PlasminMore data for this Ligand-Target Pair