BDBM50220271 1-((2R,6S)-1-(4-chlorophenylsulfonyl)-6-cyclopropylpiperidin-2-yl)cyclopropyl 4-(piperidin-1-yl)piperidine-1-carboxylate::CHEMBL400420
SMILES Clc1ccc(cc1)S(=O)(=O)N1[C@@H](CCC[C@@H]1C1(CC1)OC(=O)N1CCC(CC1)N1CCCCC1)C1CC1
InChI Key InChIKey=RJVZGMCJGORCKU-IZZNHLLZSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50220271
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.80nMAssay Description:Inhibition of gamma-secretase assessed as reduction of membrane Abeta40 levelMore data for this Ligand-Target Pair